Researcher Karthik Bodhinathan measures a mouse brain as part of his efforts to stop Alzheimer’s disease. PHOTO BY HANNA LAUKKANEN
“There aren’t very good drugs out there,” Bodhinathan explains, “and even the ones that are out, they hit multiple targets, which mean they cure what you need but also create side effects, like depression and suicidal behavior. My job is to see if we can refine them.”
Akhtar is finding out more about the link between Alzheimer's and diabetes.
“Generally,” he says, “the people with diabetes have roughly two times higher the risk of developing Alzheimer's disease.”
There are several reasons for that, he says, but the main reason centers on the sugar level in diabetic patient. High levels affect neuronal function and causes dysfunction in the powerhouses of the brain.
“In the diabetic brain, you see that they decline in learning and memory, which is what you see in an Alzheimer’s brain,” Akhtar notes.
Bodhinathan is researching the chemicals that affect the brain in prior unknown ways. It’s a big challenge, he says, because most times the drugs don’t do what researchers predict. Researchers change the chemistry, fueling a lengthy retesting process.
“I’m trying to see if we can use the brain’s different mechanism to clear these toxic proteins in the brain,” Bodhinathan says. “They attract more proteins, and they become this big gob in the brain – and we believe that once we attack those clusters, we will be able to cure the disease.”
In a related development, the U.S. Food and Drug Administration has approved Acadia Pharmaceutical’s Nuplazid drug for the treatment of hallucinations and delusions associated with Parkinson’s disease psychosis. In 2014 the FDA designated Nuplazid as a “breakthrough therapy” for this condition.
Acadia, based in San Diego, plans in June to make Nuplazid commercially available to patients suffering from hallucinations and delusions associated with Parkinson’s disease psychosis in the United States.
According to the National Parkinson Foundation, about 1 million people in the United States and from 4 to 6 million people worldwide suffer from Parkinson’s disease. An estimated 40 percent of these patients have Parkinson’s disease psychosis, characterized by hallucinations and delusions. This is associated with significant caregiver burden and is a major reason for nursing home placement among Parkinson’s patients.
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back I was having some symptoms . I went to see a doctor and many blood
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I became a little child who do nothing but to depend on others for everything, I barely move my feet and hands myself. My son, blessed memory Denis who passed on last year tried all he could to see me back on my feet but all his effort seemed to worthless. The doctor said i will have to live like that for the few days i will spend on earth. the pastor gave me hope. and prayers but it got to a time that lost my faith as my health get worst every other day
I began to await death by installment on my sick bed. but on a faithful day when i went out for my normal therapy at the clinic, my very first boy friend Stanley saw me on a wheel chair as my son pushed me in. and he came with so much expression of disappointment on his face. he stopped at nothing until he discover a herbal remedy from Dr OSEWE AGBONIFO from Africa on a post in google page.
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I am 56 years of age and was quickly diagnosed with Parkinson's 11 months ago. My symptoms are shakiness (increasing) and general reduction of control and strength of the left hand. I experienced a general tightness of the chest accompanied by periodic sudden feelings of shortness of breath. I also become quite dizzy when performing any athletic function (jogging). I was quite active . I was on Levodopa/Carbidopa, 100/25.i spent a lot of money on medication,so i decided search for permanent cure.
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Best Regards
Foster Kelis
email address: drbabaogu@gmail.com
phone no: 2348137291215
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Dr Oboi is a brave man and he is set to answer all human disease, today i am living in good health as just with a test i conquered my pain and sorrow, Please you can contact Dr Oboi for any problem with the email droboiherbscentre@gmail.com or whatsapp him on via 2349055464666