Diabetes can lead to Alzheimer’s disease, La Jolla researchers find
by HANNA LAUKKANEN
Published - 05/02/16 - 10:20 AM | 24 24 comments | 22 22 recommendations | email to a friend | print
Researcher Karthik Bodhinathan measures a mouse brain as part of his efforts to stop Alzheimer’s disease. PHOTO BY HANNA LAUKKANEN
Researcher Karthik Bodhinathan measures a mouse brain as part of his efforts to stop Alzheimer’s disease. PHOTO BY HANNA LAUKKANEN
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The workable human brain wasn’t created to last 70 to 90 years. That’s why our brains have different neurologic diseases when we age, like Parkinson's or Alzheimer's. Senior associate Karthik Bodhinathan and postdoctoral associate Mohammed Waseem Akhtar are researching new medical care for Alzheimer’s disease at La Jolla’s Sanford Burnham Prebys Medical Discovery Institute.

“There aren’t very good drugs out there,” Bodhinathan explains, “and even the ones that are out, they hit multiple targets, which mean they cure what you need but also create side effects, like depression and suicidal behavior. My job is to see if we can refine them.”

Akhtar is finding out more about the link between Alzheimer's and diabetes.

“Generally,” he says, “the people with diabetes have roughly two times higher the risk of developing Alzheimer's disease.”

There are several reasons for that, he says, but the main reason centers on the sugar level in diabetic patient. High levels affect neuronal function and causes dysfunction in the powerhouses of the brain.

“In the diabetic brain, you see that they decline in learning and memory, which is what you see in an Alzheimer’s brain,” Akhtar notes.

Bodhinathan is researching the chemicals that affect the brain in prior unknown ways. It’s a big challenge, he says, because most times the drugs don’t do what researchers predict. Researchers change the chemistry, fueling a lengthy retesting process.

“I’m trying to see if we can use the brain’s different mechanism to clear these toxic proteins in the brain,” Bodhinathan says. “They attract more proteins, and they become this big gob in the brain – and we believe that once we attack those clusters, we will be able to cure the disease.”

In a related development, the U.S. Food and Drug Administration has approved Acadia Pharmaceutical’s Nuplazid drug for the treatment of hallucinations and delusions associated with Parkinson’s disease psychosis. In 2014 the FDA designated Nuplazid as a “breakthrough therapy” for this condition.

Acadia, based in San Diego, plans in June to make Nuplazid commercially available to patients suffering from hallucinations and delusions associated with Parkinson’s disease psychosis in the United States.

According to the National Parkinson Foundation, about 1 million people in the United States and from 4 to 6 million people worldwide suffer from Parkinson’s disease. An estimated 40 percent of these patients have Parkinson’s disease psychosis, characterized by hallucinations and delusions. This is associated with significant caregiver burden and is a major reason for nursing home placement among Parkinson’s patients.

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joel lisa
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12 Hours Ago
Am Lisa by name, i was diagnosed with Herpes for 3years ago i lived in pain with the knowledge that i wasn't going to ever be well again i contacted so many herbal doctors on this issue and wasted a large sum of money but my condition never got better i was determined to get my life back so one day i saw mr Brown post on how Dr Aba saved him from the VIRUS with herbal medicine i contacted Dr Aba on his email address dr.abaherbalhome@gmail.com we spoke on the issue i told him all that i went through and he told me not to worry that everything will be fine again so he prepared the medicine and send it to me through courier service and told me how to use it,after 14days of usage I went to see the doctor for test ,then the result was negative,am the happiest woman on earth now. this testimony is real.thanks to Dr Aba God bless you. you can also reach him on his whatsApp number 2348107155060
sarahtine
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July 23, 2017
Do anyone still doubt natural herbs? I've seen the great importance of natural herbs and the wonderful work they have done in people's lives. I wonder why people still spend their money on surgery, injections and drugs each time they are sick. Natural herbs can cure all kinds of illness including herpes, diabetics, asthma, HIV, hepatitis, etc. I've seen it with my own eyes. I was cured of HIV and my aunt and her husband were cured of herpes by Dr. Baba Ogu who uses natural herbs to cure different kind of illness. Even Dr. Sebi prove to the whole world that natural herbs can cure all diseases and he cured countless of people using natural herbs. I know is hard to believe but am a living testimony. There is no harm in trying herbs. He is also a spell caster, he can cast a spell to restore your marriage back to normal, a good luck spell to prosper in life and excel in whatever you do in life. Contact or email Dr. Baba Ogu on: drbabaogu@gmail.com (phone/whatsap no): 2348137291215

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ANITA GARRY
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July 23, 2017
I am here to express my profound warm gratitude to the great ORIAREWO OSEIWE for helping me to cure my diabetes

which i have been suffering from for so long with herbs, I have never been happy like I am now, i have tried several medications to cure this diabetes all failed, i have spent a lot of money, even been scammed through this process till i got across to this great Herbalist doctor who finally have solved this problem for me now am healthy and sound,i am no longer suffering from diabetes again, he have herbs to cure cancer, diabetes and other diseases, he is the solution to diabetes diseases, i have witnessed it so i want you all to help me thank this great herbalist who have done this for me and now am living fine. God Bless you as you help save others, For My household, we would keep fighting the Good fight against diabetes worldwide. if you need his help just kindly contact him via this email: greatoriarewo@outlook.com or message him on whatsapp: 1(518)953 9485 or 2349031367320

lora james
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July 22, 2017
I want to give a testimony on how I got cured from Herpes Virus. Few months

back I was having some symptoms . I went to see a doctor and many blood

tests was done on me, later on I was told I had Herpes. My doctor told me

that there's no cure for Herpes I felt bad, I went online searching for a

possible cure for Herpes Virus, I saw a post of Dr. Amadu a herbal doctor

that's helping people get cured from HPV, HIV, HEPATITIS B, CANCER e.t.c.

ci contacted him and told him how I'm feeling he said his herbal medicine can

cure me. He sent me the medicine via Dhl delivery service and I received

the medicine some days after he sent it, i took the medicine as prescribed

by him. Before the completion of the medication the symptoms stopped. I

went to the doctor and carried out another blood test, surprisingly I was

Negative. I haven't had any symptoms anymore. Dr. Amadu is great and you can

contact via (dramaduherbalhome@gmail.com) Whatsapp him via 2349052645237;
Queen Johnson
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July 21, 2017
I can’t believe this. A great testimony that i must share to all HERPES patient in the world i never believed that their could be any complete cure for HERPES or any cure for HERPES,i saw people’s testimony on blog sites of how DR losa prepare herbal cure and brought them back to life again. i had to try it too and you can,t believe that in just few weeks i started using it all my body stop gradually and i had to leave without the HERPES DRUGS the doctor gave to me. Right now i can tell you that few months now i have not had any pain,delay in treatment leads to death. Here is his email:dr.losaherbalhome@gmail.com his WHATSAPP number is 2349050141109 or call 2349050141109 he also special on cureing 1. HIV/AIDS 2. HERPES 3. CANCER 4. ALS 5. HEPATITIS B 6. DIABETES 7. HUMAN PAPILOMA VIRUS DISEASE(HPV) 8. ALZHEIMER 9. LUPUS (Lupus Vulgaris or Lupus Erythematosus)
budemikky
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July 21, 2017
MUST READ: HOW I GOT CURED FROM MY HIV VIRUS)

Hello, My name is bude mikky, I was diagnosed of Hiv in 2014 and I have tried all possible means to get cure but all to no avail, until i saw a post in a health forum about a herbal doctor from Africa ( Dr Bello) who prepare herbal medicine to cure all kind of diseases including Herpes virus, at first i doubted if it was real but decided to give it a try, when i contact this herbal doctor via his email, he prepared a herbal medicine and sent it to me , when i received this herbal medicine, he gave me step by instructions on how to apply it, when i applied it as instructed, i was cured of this deadly virus Hiv within a week of usage I am now free from the virus, i was tasted negative. Contact this great herbal doctor via his email: bellospelltemple@gmail.com or call/whatsApp 2348147271779 when you contact him, make sure you tell him that I referenced you and Good Luck
susan loveth
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July 21, 2017
Hello everybody,

I don't just know the reason why some people is finding it difficult to believe that there is a cure for herpes, I have been suffering from herpes since last three years with my boyfriend but today I am happy that am cure from it with the herbal medicine of Dr Aba the great healer,I was browsing the internet searching for help when I came across a testimony shared by someone on how Dr Aba cure his herpes I was so much in need of getting his treatment but after all Dr Aba brought a smile to my face with his herbal medicine. I am so much happy today that we have someone like this great healer out there, so my people out there kindly contact this great healer on his email address: dr.abaherbalhome@gmail.com please sir keep your good work cause there are people out there who is in need of your healing medicine.once more contact him now: dr.abaherbalhome@gmail.com you can call him or whatsApp his number 2348107155060
Carol Anderson
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July 20, 2017
Hello everyone out there, My name is Carol Anderson. I am here to give my testimony about a doctor who helped me in my life. I was infected with HIV VIRUS in 2015, i went to many hospitals for cure but there was no solution, so I was thinking how can I get a solution out so that my body can be okay. One day I was in the river side thinking where can I go to get solution. so a lady walked to me telling me why am I so sad and i open up all to her telling her my problem, she told me that she can help me out, she introduce me to a doctor who uses herbal medication to cure HIV VIRUS and gave me his email, so i mail him. He told me all the things I need to do and also give me instructions to take, which I followed properly. Before I knew what is happening after four weeks the HIV VIRUS that was in my body got cured,I am so very much happy in my life now for the wonderful thing Dr Alabi done for me. so if you also need help to get your self cured from HIV VIRUS, you can also email him at dr.alabihivcure@gmail.com you can also call him or add him on Whats-app: 2349061385058.
joel lisa
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July 19, 2017
Am here to appreciate Dr Aba for using his herbal medicine to cure my Herpes virus. since 3 years now I have been living with this virus and it has been giving me challenges, I was so perplexed cause i have been taking several drugs to be cured but all of my effort was in vain,one morning i was browsing through the internet then i saw several testimonies about Dr. Aba curing people from Herpes virus and immediately i contacted Dr. Aba on his email: dr.abaherbalhome@gmail.com, i told him about my troubles and he told me that i must be cured, gave me some instructions and which i rightly followed. so he prepared a herbal medicine for me and sent it to me which i used for 2 weeks and everything was like a dream to me and my Herpes virus was totally gone, why don't you contact him today and be free from your diseases because he is very good and honest Doctor. contact him via email; dr.abaherbalhome@gmail.com or whatsApp him on 2348107155060
Donnie56778
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July 17, 2017
My husband is 80 years and has been suffering from PD for the past 15 years. Lately he started hallucinating and I didn't know how to handle the situation. He cannot sleep and tried to find and catch the imaginary people who he thinks are real. he was taken Entacapone with Levodopa, Carbidopa, and Pramipexole and started physical therapy to strengthen muscles. nothing was really working to help his condition.I took him off the Siferol (with the doctor’s knowledge) and started him on parkinson’s herbal formula i ordered from Health Herbal Clinic, his symptoms totally declined over a 5 weeks use of the Parkinsons disease natural herbal formula.i read reviews from other previous patients who used the herbal formula, my husband is now active, he can now go about daily exercise!! his symptoms so much reduced that now I hardly notice them.Visit there website www. healthherbalclinicc. weebly. com or email Info@ healthherbalclinic. net
jessica ana
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July 17, 2017
Am here to appreciate Dr Aba for using his herbal medicine to cure my Herpes virus. since 3 years now I have been living with this virus and it has been giving me challenges, I was so perplexed cause i have been taking several drugs to be cured but all of my effort was in vain,one morning i was browsing through the internet then i saw several testimonies about Dr. Aba curing people from Herpes virus and immediately i contacted Dr. Aba on his email: dr.abaherbalhome@gmail.com, i told him about my troubles and he told me that i must be cured, gave me some instructions and which i rightly followed. so he prepared a herbal medicine for me and sent it to me which i used for 2 weeks and everything was like a dream to me and my Herpes virus was totally gone, why don't you contact him today and be free from your diseases because he is very good and honest Doctor. contact him via email; dr.abaherbalhome@gmail.com or whatsApp him on 2348107155060
Helen Gibson
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July 12, 2017
MY ALS STORY

To live is more important than to die. Even with less hope or fortune. For a living dog is better than a dead lion.

My name is Helen Gibson and I am from Canada, by the grace of God almighty I will be clocking 79yrs this November. it all started the year 2014 when i was diagnosed of amyotrophic lateral sclerosis [ALS].



I became a little child who do nothing but to depend on others for everything, I barely move my feet and hands myself. My son, blessed memory Denis who passed on last year tried all he could to see me back on my feet but all his effort seemed to worthless. The doctor said i will have to live like that for the few days i will spend on earth. the pastor gave me hope. and prayers but it got to a time that lost my faith as my health get worst every other day

I began to await death by installment on my sick bed. but on a faithful day when i went out for my normal therapy at the clinic, my very first boy friend Stanley saw me on a wheel chair as my son pushed me in. and he came with so much expression of disappointment on his face. he stopped at nothing until he discover a herbal remedy from Dr OSEWE AGBONIFO from Africa on a post in google page.

Dr osewe told me that he have herbal cure for the following diseases; HIV AIDS, ALS, MND, Epilepsy, Leukemia, Asthma, Cancer, Candida, Gonorrhea,Empty stomach[yin infection] even spell to secure what ever you desire like [lover, job,and fortune i.e wealth without limit e.t.c] cleansing spell, spiritual fortification. spell to gain power and become number one priority over others. gave me reasons to give him a try which i did not because i believed or trust him but because i was left with no choice. He prepared herbal portion and send it across to me on negotiation, he gave me instructions which my son took seriously. After three[3] of treatment i began to notice some changes which gave me courage to send for more of the herbal portion.

THE KEY POINT IS THAT I CAN DO THINGS NOW WITHOUT NEEDING SUPPORT OR BUGGING ANYBODY.

Dr osewe never asked me to advertise him but i think it's what i should do to make our world a favourable and disease free one. contact him today @ oseweagbonifo@gmail.com or call his tel; 2348135123287. I so much love this man for i owe my life to him.
FOSTERWEG
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July 05, 2017


I am 56 years of age and was quickly diagnosed with Parkinson's 11 months ago. My symptoms are shakiness (increasing) and general reduction of control and strength of the left hand. I experienced a general tightness of the chest accompanied by periodic sudden feelings of shortness of breath. I also become quite dizzy when performing any athletic function (jogging). I was quite active . I was on Levodopa/Carbidopa, 100/25.i spent a lot of money on medication,so i decided search for permanent cure.

One faithful day on the internet I saw some post's about perfecthealthherbalmedicinehome,so many people was talking about their herbal medicine that they cures different kinds of deadly diseases,so i decided to give it a try ,i contacted them via their email,(perfecthealthherbalmedicine @ gmail'com) website;(www'perfecthealthherbal'weebly'com),so they replied me,and told me that they will cure me within 5-6 weeks ,then i purchased the herbal medicine and they sent the herbal medicine to me via courier service,which i received within 2days.so after 5 weeks of usage all my symptoms disappeared totally ,then i went for medical check-up and doctor confirmed i am totally cured and parkinson's diseases free.so please viewers my testimony is a true life story,all thanks to perfecthealthherbalmedicinehome...

Best Regards

Foster Kelis

Sarahtine4521
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June 28, 2017
I was cured of HIV with the used of natural herbs. My name is Sarah and am from US. I love herbs so much. Most times, injection and drugs are just a waste of time. I was cured 8months ago, i suffered from HIV for 13yrs but with the help of DR. Baba Ogu herbal medicine, i was cured within few weeks of drinking the herbs he sent to me through courier delivery service. This same doctor also cured my Aunty from herpes, as soon as i heard she had herpes, i quickly refer her to Dr. Baba Ogu and she was cured too after drinking his herbs.I have referred more than 15 persons to Dr. Baba Ogu and they were all cured from their various illness. Have you taken herbs before?. You have spent so much money on drugs,injections,surgeries etc and yet you have no good result to show for it. Contact Dr. Baba Ogu now, he is a herbalist doctor, i assured you of a cure if you drink his natural herbs. Dr Baba Ogu have herbs that cures Hiv, Herpes, diabetics, asthma, hepatitis, HBP, STD, cancer, chronic, etc. Contact Dr. Baba Ogu on:

email address: drbabaogu@gmail.com

phone no: 2348137291215

whatsap no: 2348137291215

facebook.com/drbabaogucure/
erica thompson
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July 04, 2017
Hi friends!

I am Erica Thompson by name and i want to use this great opportunity to share with you some great and amazing testimony of how i was cured from HERPES Virus with the help of Dr oboi Herbal Medicine.

Over 2 years now i have been suffering and living in pain with this deadly virus Herpes, fear grew in my mind everyday as i heard there is no cure for it, but to me i knew that medical drugs was not the only option in treating viruses and infection, my greatest problem was that i was stocked in pain as the symptoms has circulated over my body.

Few Months ago i decided to get more information online concerning herpes,and while i was surfing the web, i came across some great testimonials from various people on how Dr oboi has been using his herbal medicine to cure different disease, at first i was shocked as i have never heard of such thing before, and also i doubted if it was true as it never came up on media, these people gave out the email address of Dr oboi and advised we contact him for any problem, though i was doubting him i decided to put a test on it, moreover it was the fist time for me to hear something like that, i copied the email address of Dr oboi and i sent him a message about my health status and i also requested for his medicine in order for me to get good health, he gave me a responded after some hours and he told me the procedure involved in order for me to get his medicine, he also said to me he was going to send me some herbal liquid medicine which was going to take for 2 weeks and after 2 weeks i will be totally cured.

I went with Dr Oboi and i followed exactly as i was told by this man, after 3 to 5 days of communication i eventually received a package from the mailing service and that was the medicine sent by Dr oboi

I started taking the medicine as i was directed by Dr oboi and after 2 weeks i also started seen some changes on my skin, and after a month passed i noticed that the rashes on my skin are cleared, i was surprised and i had a thought to myself again LIKE! IS THIS REALLY WORKING OUT? when i noticed this changes i contacted this Great Dr and i told him about it, he told me to go to the hospital and do some check up if the virus is still there, i actually went to the hospital on Friday to do some test on my blood and after 3 days the result came out that i was completely free from HERPES, still many people will not believe this, but it did really works.

Dr Oboi is a brave man and he is set to answer all human disease, today i am living in good health as just with a test i conquered my pain and sorrow, Please you can contact Dr Oboi for any problem with the email droboiherbscentre@gmail.com or whatsapp him on via 2349055464666
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